Antibiotics

Polymyxins

Colistat (Сolistin)
Powder for solution for intravenous injection and inhalations 2 000 000 ME

Reliable choice in treatment of acquired microbial resistance. Especially active against gram-negative (-) bacteria. Most active against Pseudomonas aeruginosa, Acinetobacter baumannii, Citrobacter spp. Used parenterally in treatment of serious infections of lower respiratory tract and urinary system when widely used systemic antibiotics are ineffective because of development of bacterial resistance. Inhalational administration is recommended for patients with mucoviscidosis.

Carbapenems

Dorenem (Doripenem)
Powder for solution for infusion 500 mg

A highly potent carbapenem antibiotic drug. Active against gram-positive (+) and gram-negative (-) aerobic and anaerobic bacteria. Several times more active against Pseudomonas aeruginosa compared to meropenem and imipenem/cilastatin. Used in treatment of hospital-acquired (nosocomial) pneumonia, including ventilator-associated pneumonia; complicated intraabdominal infections; complicated infections of urinary system, including complicated and uncomplicated pyelonephritis, particularly pyelonephritis with accompanying bacteremia.

Meropenem-TF (Мeropenem)
Powder for solution for intravenous injection 500 mg, 1000 mg

An ultra-wide range of antibacterial activity includes practically all significant gram-positive (+) and gram-negative (-) aerobic and anaerobic microorganisms. Non-neurotoxic. Used for de-escalation therapy of serious infections of lower respiratory tract, intraabdominal infections, gynecological infections, skin and soft tissue infections, meningitis, septicemia, empiric treatment in patients with neutropenia, as monotherapy or in combination with antiviral or antifungal pharmaceutical products.

Imicinem-TF (Imipenem/cilastatin)
Powder for solution for intravenous injection 250 mg/250 mg, 500 mg/500 mg

“Gold standard” of monotherapy of serious infections in inpatient settings.

Active against a wide range of gram-positive (+) and gram-negative aerobic bacteria, majority of anaerobic bacteria.

Used in therapy of serious polymicrobic infections of lower respiratory tract, urinary system infections, intraabdominal infections, gynecological infections, skin and soft tissue infections, bone and joint infections, endocarditis.

glycopeptides

Teicoplanin-TF (Teicoplanin)
Powder for solution for intravenous and intramuscular injection 200 mg, 400 mg

New highly effective glycopeptide antibiotic for systemic use with bactericidal activity against a wide range of gram-positive (+) bacteria, multiresistant nosocomial strains, including VanB-phenotype VRE. It can be administered once daily intramuscularly or intravenously as a bolus injection. The antibiotic has low toxicity and favorable tolerability. It is used in treatment of serious respiratory and urinary tract infections, skin and soft tissue infections, bone and joint infections, septicemia, endocarditis, peritonitis, infectious colitis.

Vancomycin-TF (Vancomycin)
Powder for solution for infusion 500 mg, 1000 mg

First antibiotic of the glycopeptide group. Highly active against a wide range of gram-positive (+) microorganisms, including methicillin-resistant strains.

Used in treatment of endocarditis, sepsis, skin and soft tissue infections, bone and joint infections (including osteomyelitis), CNS infections (including meningitis), infections of lower respiratory tract, pseudomembranous colitis, enterocolitis.

Cephalosporins Generation IV

Cefepime-TF (Cefepime)
Powder for solution for intravenous and intramuscular injection 500 mg, 1 g

Antibiotic with an extra-wide range of activity (gram-positive (+) and gram-negative (-) aerobes and anaerobes). Resistant to β-lactamases. Characterized by low incidence of adverse reactions. Used in treatment of serious respiratory tract infections, urinary tract infections (including pyelonephritis), skin and soft tissue infections, intraabdominal, gynecologic infections, septicemia, neutropenic fever, bacterial meningitis in children.

 

Cephalosporins Generation III

Trixocef (Ceftriaxone)
Powder for solution for intravenous and intramuscular injection 500 mg, 1000 mg

Wide range of antibacterial activity (gram-positive (+) and gram-negative (-) aerobes), resistance to β-lactamases, low incidence of adverse reactions.

Used in hospital and outpatient practice for treatment of infections of ENT organs, infections of upper and lower respiratory tract, skin and soft tissue infections, bone and joint infections, infections of abdominal cavity organs, infections of pelvic organs and urinary tracts, bacterial meningitis, sepsis, disseminated Lyme borreliosis, infections of genital organs, including gonorrhea.

Cefosulbactam (Cefoperazone/Sulbactam)
Powder for solution for intravenous and intramuscular injection 1000 mg/1000 mg

“Protected” third-generation cephalosporin in combination with β-lactamase inhibitor. Wide range of antibacterial activity against clinically significant gram-positive (+) and gram-negative (-) aerobic and anaerobic microorganisms.

Used as monotherapy for treatment of serious infections of upper and lower respiratory tract, peritonitis, cholecystitis, cholangitis and other intraabdominal infections, infections of genital organs, including gonorrhea. Well-tolerated when administered intravenously.

Противотуберкулезное средство

Capreocin (Capreomycin)
Powder for solution for intravenous and intramuscular injection 1000 mg

Antituberculous polypeptide antibiotic drug of low toxicity with favorable tolerability. Used in therapy of drug-resistant forms of pulmonary tuberculosis.